Clinical Chemistry Podcast RSS
Summary: This free monthly podcast is part of Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory. In addition to being the most cited journal in the field (26,500 citations in 2014), Clinical Chemistry has the highest Impact Factor (7.9 in 2014) among journals of clinical chemistry, clinical (or anatomic) pathology, analytical chemistry, and the subspecialties, such as transfusion medicine, clinical microbiology.
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This is the August 2015 issue of Clinical Chemistry, Volume 61, Issue 8.
Advances in clinical laboratory testing have had a profound impact in improving the quality of medical care. Today laboratory diagnostic tests inform physicians and patients of the exact causes of a number of diseases and disorders, including cancer, chronic diseases, infectious diseases, sexually transmitted diseases, and genetic disorders.
In the past decade there has been a rapid increase in the number of individuals who have had their entire genome sequenced. Over the next decade that number will go from the thousands to the millions. These people are having their genomes sequenced for research, recreational interest, and clinical testing.
Vitamin D insufficiency has been widely associated with numerous negative health outcomes, including higher all-cause mortality, although no mechanism has been formally established for such observations.
This is the July 2015 issue of Clinical Chemistry, Volume 61, Issue 7.
Clinical trials, epidemiologic and most types of clinical research, include the acquisition of biological samples to be analyzed either immediately after collection, or in the future for biomarkers related to the study hypotheses. Tested biomarkers include those used to monitor subjects' health and to detect harmful side effects or to follow impact of therapeutic interventions.
This is the June 2015 issue of Clinical Chemistry, Volume 61, Issue 5.
In October of 2010, the U.S. Food and Drug Administration approved a new oral direct thrombin inhibitor for prevention of stroke and thrombosis in patients with atrial fibrillation. This marked a new era in the development of fixed dose novel oral anticoagulants, with a hope of achieving improved safety and clinical outcomes compared to warfarin.
This is the May 2015 issue of Clinical Chemistry, Volume 61, Issue 5.
A major objective of the International Federation of Clinical Chemistry and Laboratory Medicine, or IFCC, Task Force on implementation of Hemoglobin A1c Standardization is to develop quality targets with the measurement of Hemoglobin A1c.
Medical laboratories provide valuable services to aid in patient diagnosis and management, but systematic evidence of laboratory medicine's specific contribution to the overall process of healthcare is not easy to come by. Even the widely quoted claim that laboratory medicine results are responsible for a 70% of all clinical decisions seems to elude objective verification.
Over the past 20 years or so there have been several studies published showing an association between decreased concentrations of vitamin D in blood and the risks of cardiovascular disease, stroke, cancer, fractures, even overall mortality.
This is the April 2015 issue of Clinical Chemistry, Volume 61, Issue 4.
Rapid urine pregnancy tests have been available for over 30 years. They can be performed in minutes and are used at home, in doctors' offices and in emergency rooms. Doctors in particular rely on these tests to rule out pregnancy in order to prevent fetal injury or death that could be caused by certain medical procedures or drugs.
Recently, the New England Journal of Medicine partnered with Area9 Learning, a physician-led pioneer in adaptive learning, to create a platform with smart technology that adapts to clinicians' learning goals and knowledge gaps to deliver the information they need to know.