Clinical Chemistry Podcast RSS
Summary: This free monthly podcast is part of Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory. In addition to being the most cited journal in the field (26,500 citations in 2014), Clinical Chemistry has the highest Impact Factor (7.9 in 2014) among journals of clinical chemistry, clinical (or anatomic) pathology, analytical chemistry, and the subspecialties, such as transfusion medicine, clinical microbiology.
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- Artist: American Association for Clinical Chemistry
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The authors of this study used a 46 gene qPCR panel for the characterization of circulating tumor cells from metastatic breast cancer patients undergoing palliative therapy.
There are profound differences between the sexes regarding cardiac physiology and the development of heart disease.
We wished to assess the frequency of overinterpretation in systematic reviews of diagnostic accuracy studies.
We currently live in an age of massive personal data creation through activities such as social media, online banking, and healthcare.
Transgender is an umbrella term used to describe individuals who identify with a gender incongruent to or variant from their sex recorded at birth.
Although the introduction of prospective trial registration policies has been successful in reducing waste in research, diagnostic accuracy studies are rarely registered.
The rapid identification of respiratory pathogens is important for providing targeted rather than empiric therapy.
The importance of standardization of laboratory test results has a long history traceable to the first proficiency testing results in 1947 that demonstrated large discrepancies among results from 59 hospital laboratories.
There are conflicting data on whether changes in N-terminal pro–B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hs-CRP) concentrations between time points (delta NT-proBNP and hs-CRP) are associated with a change in prognosis.
Cardiac troponin T (cTnT) is an acknowledged biomarker of acute myocardial infarction (AMI) that is known to be prone to proteolytic degradation in serum. Such degradation is usually explained by the action of μ-calpain, although there could be other candidates for that role. In the current study, we explored the hypothesis that thrombin-mediated cTnT cleavage occurs as a result of the serum sample preparation.
DB-PINACA and its 5-fluoropentyl analog 5F-ADB-PINACA are among the most potent synthetic cannabinoids tested to date, with several severe intoxication cases. ADB-PINACA and 5F-ADB-PINACA have a different legal status, depending on the country.
This is the June 2017 issue of Clinical Chemistry, Volume 63, Issue 6.
This is the May 2017 issue of Clinical Chemistry, Volume 63, Issue 5.
The neonatologist and pediatric gastroenterologist see different shades of yellow in newborns. The neonatologist sees yellow in the context of the Bhutani plot, which defines triggers for phototherapy or transfusion based on total bilirubin concentrations in the first 5 days of life (1).
Being able to target specific therapies to specific disease entities is the goal of all precision medical initiatives. Such approaches have been implemented in malignancies with individual examples of great responses. Such successes have fueled enthusiasm to apply this approach to other forms of chronic disease.
