You're the Expert

Dr. Mande Holford studies venomous sea snails, the "assassins of the sea." Her research holds clues to treating Alzheimer's, solving opioid addiction, and much more. Panelists Tracy Clayton (Another Round), Zhubin Parang (head writer for The Daily Show), and author Maeve Higgins learn about the mysterious world of these underwater killers. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Did you know that you're about 2% Neanderthal? Bridget Alex is a Harvard anthropologist and evolutionary biologist studying how/when our ancestors met and bred with Neanderthals. She teaches comedians Sam Ike, Kenice Mobley, and Steve Macone about the mysteries of evolution and a caveman's love life. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Dr. Noah Wilson-Rich is the chief scientific officer at the Best Bees Company. Comedians Bobby Smithney, Julia Claire, and Gary Petersen learn about Noah's research and dive into the secret lives of bees, what it's like to be stung 500 times, and why it's good to be the queen. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Dr. Gary Fireman is the chair of Suffolk University's Psychology Department. He's an expert on nightmares and disturbed dreaming. Comedians Maeve Higgins, Charlie Hankin, and Matt Porter find out where nightmares come from, what they mean, and how they compare to an acid trip. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Natalie Reeder is the official wildlife biologist at San Francisco International Airport. Natalie helps comedians Kristen Schaal, Eugene Mirman, and James Adomian understand how to keep birds away from engines, when snakes actually do get out on planes, and why SFO is full of frogs. Recorded in front of a live audience at SF Sketchfest 2016. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Dr. Jean Alupay is an octopus expert at USC. Comedians Scott Adsit (30 Rock), Emily Maya Mills (Parks and Rec), and Josh Sharp (CBS) try to guess what Dr. Alupay studies and learn the mysteries of the deep. Whether you're a human or a three-hearted boneless sea creature, this episode is for you. Hosted by Chris Duffy. Produced by Pretty Good Friends. Recorded in front of a live audience at the Nerdist Showroom in Los Angeles, CA. 

Eugene Mirman, Scott Adsit, and Maeve Higgins learn from Dr. Leslie Dewan, an MIT alum who developed a revolutionary new nuclear reactor that's powered by nuclear waste. It's environmentally friendly, cheaper than other reactors, and it can't meltdown. She's kind of a big deal. Along the way, we learn about the social life of nuclear engineers, why BP really needs some new recruiting videos, and Guy Fieri's cooking. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Live from the Bell House in Brooklyn, this is a special NYSW edition of the show. Dr. Melanie Stiassny, an ichthyologist at the American Museum of Natural History, teaches comedians Scott Adsit, Jo Firestone, and Josh Gondelman about the mysteries of the ocean (and what happens at a museum after hours). Hosted by Chris Duffy. Produced by Pretty Good Friends.       

What's inside of a black hole? How do you measure the universe? What was the first vegetable grown in space? We dive deep into these questions and more with Dr. Anca Constantin from James Madison University's Physics and Astronomy Department. Featuring comedians Maeve Higgins, Anna Drezen, and Nick Vatterott. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Live from the 2015 Bay Area Science Festival, this episode features UC Berkeley's Lindsey Dougherty, a marine biologist who studies disco clams, which light up underwater. Lindsey's trying to figure out why and how these clams act like underwater disco balls. Trying to guess what she studies and learning why it's important are comedians W. Kamau Bell (CNN's "United Shades of America), Kurt Braunohler (Comedy Central), and Emmy Blotnick (@Midnight). Hosted by Chris Duffy. Produced by Pretty Good Friends.

Nate Fuller studies bats. In this special Halloween show, we go deep into caves full of guano, get bitten by vampire bats, and hear about some extremely unusual first dates. Featuring comedians Jo Firestone, Josh Sharp, and Ken Reid. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Harvard Medical School's Dr. Jo Shapiro joins us to talk about her work as a throat surgeon and the head of Brigham and Women's Hospital's Center for Professionalism and Peer Support. Panelists Eugene Mirman, Scott Adsit, and Jo Firestone learn about the beautiful anatomy of the throat, the emotional stress of being a doctor, and why it can be dangerous to eat steak at a Florida IHOP. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Ammon Shea has read the entire Oxford English Dictionary and the phone book cover-to-cover and written books of his own about each. In this special book festival edition of the show, we cover exotic words, the most expensive phone book in the world, and how to use etymology as a pick up line. Hosted by Chris Duffy. Produced by Julie Smith Clem and Pretty Good Friends.

Joseph Bagley is the official Boston City Archaeologist. He's in charge of preserving Boston's many historic sites, but his real passion is digging up outhouses and privies to discover what secrets they contain. Panelists Steve Almond, Myq Kaplan, and Bethany Van Delft try to get the dirt on Joe's research and learn about looting, chowder, and bowling ball based crimes. Hosted by Chris Duffy. Produced by Pretty Good Friends.

Dr. Alexandra Horowitz is the head of Barnard's Canine Cognition Lab. She's also our first ever repeat guest! She was so great the first time, we had to have her on again with our new format. Panelists Mara Wilson, H. Jon Benjamin, and Josh Gondelman try to guess what Alexandra studies and then interview her about her work. Learn the truth about alpha males, guilty dog faces, and what a dog sees in the mirror. Hosted by Chris Duffy. Produced by Pretty Good Friends.