Summary: Dr Michael Harrison discusses pathology testing in the tired patient with Dr Kathryn O'Connor. International guidelines on pathology testing in the tired patient vary and all are consensus rather than evidence based. Dr Harrison discusses the incidence of tiredness, the pick up rate of serious disease for pathology testing in the tired patient and other important reasons for decisions about testing in the general practice setting. He explains that, despite the fact that best practice eludes definition, it is possible to be rational in our approach to this problem
