Martin R. Farlow, MD - Scientific and Clinical Frontiers in the Treatment of Alzheimer’s Disease: Identification of Novel Pathways and Development of New Treatments

Summary: This 2-part activity focuses on some of the pathological and clinical aspects related to regional cerebral hypometabolism in patients with Alzheimer’s disease. Part 1 includes a brief discussion of key concepts of the underlying pathophysiology of Alzheimer’s disease and a review of the aspects of cerebral hypometabolism, including genetic polymorphisms, hypothesized pathological mechanisms, and potential treatments. The second part of the activity summarizes recent clinical data related to potential treatments to improve cognitive function in Alzheimer’s disease by overcoming cerebral hypometabolism.