Summary: April 13, 2008: #45 Guest Dr Ray DePaulo on Treatment-Resistant Depression Topics include: # Treatment-Resistant Depression. How is it defined (~10:00 min into the podcast)? Is there a magic bullet? Treatment strategies (don't give up; remember lithium; use proven agents; get 2nd and 3rd opinions; do psychotherapy). # Nellie, the Hypothetical Patient. Let her know what we know about treatment and what we don't. # "Alternative" Treatments. St. John's wort; SAMe (s-adenosylmethionine); omega-3 fatty acids; ketamine; vagal nerve stimulation (VNS); deep brain stimulation (DBS); psychosurgery (cingulotomy). # Cognitive Therapy. Many different types. # Words which are Unliked by the Podcasters. Alternative treatment. Mood stabilizer. Antidepressant. Antipsychotic. Hallucinogen. Psychosis. Neurosis. Organic. Schizophrenia. Nervous breakdown. Mood Swings. # Quotations We Like. "There's only two types of music: good music and bad music," by Fran Liebowitz. "Eighty percent of success is showing up," by Woody Allen. For the rest of the quotes, see the Show Notes at mythreeshrinks.com. # Drugs in the Drinking Water. Brief mention of last month's AP story finding all sorts of pharmaceuticals in numerous municipal water supplies. # Books we are reading. -Ray: "Saint Augustine", by Garry Wills. -Roy: "Valis", by Philip K. Dick. (Ben was reading it on "Lost".) -Clink: Listening to an opera about Carmen, a famous female sociopath. -Dinah: "How Doctors Think", by Jerome Groopman. Dr. DePaulo's most recent book is Understanding Depression. Send us your general questions at mythreeshrinksATgmailDOTcom.Go to http://mythreeshrinks.com for show notes with links.
