Summary: On this podcast episode, I discuss darifenacin pharmacology, adverse effects, drug interactions and much more. <br> <br> <br> <br> CYP3A4 and CYP2D6 are important enzymes in relation to darifenacin. I breakdown the importance of these enzymes and how they can impact drug therapy. <br> <br> <br> <br> Darifenacin has anticholinergic activity but affects the central nervous system less than other agents in its class such as oxybutynin and tolterodine. <br> <br> <br> <br> Darifenacin's pharmacology is selective for the Muscarinic-3 (M3) receptor in bladder tissue which helps reduce the risk for CNS adverse effects.
