Summary: On this episode, I discuss esomeprazole (Nexium) pharmacology, adverse effects, tapering, kinetics, and drug interactions. <br> <br> <br> <br> I spend a good amount of time discussing the esomeprazole and clopidogrel interaction in this podcast episode. <br> <br> <br> <br> Esomeprazole inhibits CYP2C19. This can cause an increase in citalopram concentrations and raise the potential for QTc prolongation. <br> <br> <br> <br> It is critical to reassess the length of therapy and the dose of PPIs like esomeprazole.
