Summary: Lansoprazole is a proton pump inhibitor that can be commonly used for GERD, PUD, and GI prophylaxis.<br> <br> <br> <br> Lansoprazole can inhibit CYP2C19 which can cause concentrations of drugs like escitalopram and citalopram to rise.<br> <br> <br> <br> Hypomagnesemia, low B12, osteoporosis, and an increase in C. Diff risk are potential complications with longer-term PPI use.<br> <br> <br> <br> PPIs like lansoprazole are best given 30-60 minutes before meals. This is something that patients often forget.<br> <br> <br> <br> I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.<br> <br> <br> <br> Be sure to check out our free Top 200 study guide – a 31-page PDF that is yours for FREE!
