Summary: On this episode I discuss roflumilast (Daliresp) pharmacology, adverse effects, and important drug interactions. <br> <br> <br> <br> Roflumilast is indicated to reduce the incidence of COPD exacerbations. <br> <br> <br> <br> Roflumilast is significantly broken down by CYP3A4 so there are numerous drug interactions that we have to take into account. <br> <br> <br> <br> Psychiatric issues, GI upset, and weight loss are all potential adverse effects due to roflumilast.
