Grapefruit Juice Interactions




Real Life Pharmacology - Pharmacology Education for Health Care Professionals show

Summary: On this episode of the podcast, I discuss my approach and strategies to handle grapefruit juice interactions. <br> <br> <br> <br> Grapefruit juice causes drug interactions by inhibiting the CYP enzyme system. More specifically, it inhibits CYP3A4 which is responsible for the breakdown of many medications.<br> <br> <br> <br> Quantity is always an important consideration when assessing grapefruit juice interactions. The more that is taken, typically, the more drug concentrations will be affected.<br> <br> <br> <br> It is important to assess the use of grapefruit juice when your patient has a history of cardiovascular disease, cardiac conditions, pain, mental health disease, or gout as some medications used to treat these diseases can interact with grapefruit juice. <br> <br> <br> <br> If you are looking for more content on drug food interactions, be sure to check out my book in the links below.