Summary: Featuring articles on efficacy of the ChAdOx1 nCoV-19 vaccine against the B.1.351 variant, NVX-CoV2373 vaccine efficacy against B.1.351 in South Africa, endovascular therapy for basilar-artery stroke, intensive or standard blood-pressure control, and on gene editing for congenital neutropenia; a review article on monoclonal gammopathy of renal significance; a case report of a woman with nausea, diarrhea, and acute kidney failure; and Perspective articles on minority tax reform, on training future health justice leaders, and on finding a way to break through the fog. Supplement to the New England Journal of Medicine, Vol. 384, No. 20.
