Summary: Hyoscyamine is an anticholinergic medication that is primarily used for GI problems like spasms and pain associated with IBS.<br> <br> <br> <br> Because of the highly anticholinergic nature of hyoscyamine, it can cause dry eyes, dry mouth, urinary retention, and constipation.<br> <br> <br> <br> Be aware of the risk for the prescribing cascade with hyoscyamine. Saliva substitutes for dry mouth, artificial tears for dry eyes, etc.<br> <br> <br> <br> Sedation is a concern with hyoscyamine and this can be exacerbated by drugs like benzodiazepines, opioids, and older antihistamines.
