April 2017: deconstructing dilemmas in Amyotrophic Lateral Sclerosis and Guillain-Barré Syndrome

Summary: Both patient and editor's choices are discussed in this monthly episode of the JNNP podcast. The clinical care of patients with Guillain-Barré syndrome (GBS) can often be complex; a disease with a highly variable clinical course. Professor Bart Jacobs, from the Department of Neurology at Erasmus Medical Centre (Rotterdam) provides an overview of some of the dilemmas that may arise when treating patients with GBS. The full article: http://jnnp.bmj.com/content/88/4/346. In the second part of this podcast: The C9orf72 repeat expansion is reported to have a negative impact on prognosis in amyotrophic lateral sclerosis (ALS). Until now, researchers have not been able to examine the relationship between C9orf72 and factors such as age, site of onset or gender. Dr James Rooney discusses how he and colleagues examined the prognostic impact of the C9orf72 repeat expansion in more detail. <p>The full article is available here: http://jnnp.bmj.com/content/88/4/281.1.</p>