Linezolid Pharmacology




Real Life Pharmacology - Pharmacology Education for Health Care Professionals show

Summary: Linezolid is an antibiotic used for bacterial infection. It primarily works by inhibiting bacterial protein synthesis.<br> <br> <br> <br> Linezolid is primarily bacteriostatic against most bacteria which means that it inhibits the growth and doesn't necessarily kill the bacteria itself.<br> <br> <br> <br> Caution must be used with linezolid and serotonergic drugs as there is a risk for serotonin syndrome. Clinical risk/benefit analysis needs to be done.<br> <br> <br> <br> Linezolid overall has good coverage for VRE and MRSA. It is an option for MRSA pneumonia where daptomycin is not.<br> <br> <br> <br> Linezolid has both an oral and an IV option which allows for good continuity of inpatient and outpatient use.