Summary: On this episode I breakdown nitrofurantoin pharmacology. Nitrofurantoin is an antibiotic that is used in the treatment of UTI's.<br> <br> <br> <br> Nitrofurantoin has activity by creating reactive metabolites that can disrupt protein synthesis and ultimately kills the bacteria causing the infection.<br> <br> <br> <br> It is important to remember with nitrofurantoin, that in the setting of systemic infection and/or kidney involvement, the drug may not be very effective.<br> <br> <br> <br> Nitrofurantoin can potentially reduce the effectiveness of certain vaccines. Be sure to look this up prior to administration.<br> <br> <br> <br> Nitrofurantoin can cause pulmonary symptoms as well as neuropathy. This is very important to monitor for.
