![NEJM This Week show](https://d3dthqtvwic6y7.cloudfront.net/podcast-covers/000/030/838/small/nejm-this-week-audio-summaries.jpg)
Summary: Featuring articles on alteplase for stroke with unknown onset; smoking cessation, weight, diabetes, and mortality; risk factors and cardiovascular outcomes in type 2 diabetes; ibalizumab for HIV-1 treatment; and biosensing internal bleeding; a review article on hypertrophic cardiomyopathy; a case report of a man with syncope; and Perspective articles on the parenteral opioid shortage, on fractional-dose yellow fever vaccination, and on lessons from an angry patient.