Summary: 1. Diagnosing Cerebral Ischemia with Door-to-Thrombolysis Times Below 20 Minutes 2. What’s Trending: Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke Dr. Jimmy Berthaud speaks with Drs. Olli Mattila and Perttu Lindsberg about their paper on the accuracy and consequences of rapid stroke diagnostics in a neurological emergency department. In the second segment of the podcast, Dr. Kevin Barrett interviews Dr. Bruce Campbell about the EXTEND-IA TNK trial of tenecteplase for patients with ischemic stroke. DISCLOSURES: Dr. Berthaud reports no disclosures. Dr. Mattila has recieved research support from the Maire Taponen Foundation, The Finnish Medical Foundation, The Finnish Foundation for Cardiovascular Research, Inkeri and Mauri Vänskä Foundation, and the Aarne and Aili Turunen Foundation. Dr. Lindsberg serves as Assistant Editor for the medical journal DUODECIM; serves as chairman of the ad hoc committee on Current Therapy Guidelines in Stroke for the Finnish Medical Society; and has recieved research support for Helsinki University Hospital District, the Sigrid Jusélius Foundation, the Jane and Aatos Erkko Foundation, and the Signe and Ane Gyllenberg Foundation. Dr. Barrett has received research support from Axovant Sciences, Inc., the Virginia Center of Alzheimer's and Related Diseases, and the Department of Defense. Dr. Campbell serves on the editorial board for Stroke Stroke; served as PI of the EXTEND-IA trial, partially funded by unrestricted grant from Medtronic; and has received research support from the National Health and Medical Research Council of Australia (GNT1111972 2016-2019) and the Heart Foundation, Australia.
