Summary: <p>Professor Emeritus Andrew Eisen (University of British Columbia, Canada) discusses the theory of corticofugal primary in amyotrophic lateral sclerosis. ALS can be viewed as a primarily human disorder mediated by corticomotorneuronal pathways, originating in the cerebral cortex. Read the full paper here: http://jnnp.bmj.com/content/88/11/917.</p>
