George W. Sledge, MD - Update on Antiangiogenic Therapy in Metastatic Breast Cancer: Recent Advances, Clinical Issues, and Future Directions

Summary: In this panel discussion, experts present up-to-date data on antiangiogenic therapies in breast cancer. Recent clinical data on antiangiogenic therapy in metastatic breast cancer are reviewed, and implications for clinical practice and research are discussed. The potential benefits of targeting multiple pathways in breast cancer, by using a combination of antiangiogenic and other biologic agents or novel multitargeted therapies with antiangiogenic properties, are described. As well, strategies for optimal integration of antiangiogenic agents into treatment of breast cancer in the context of other cytotoxic and biologic therapies are discussed.