TB special: The ins and outs of interferon-gamma release assays




Thorax podcast show

Summary: We are delighted to present a podcast recording of an interview with Professor Ajit Lalvani to coincide with the TB special edition of Thorax in March. He describes the development of the FDA-approved, NICE and CDC-endorsed interferon-gamma release assay (IGRA, ELISpot, T-SPOT.TB) which he invented and validated as the first advance in diagnosis of latent TB in 100-years. He will discuss new findings using this assay published in the March issue of Thorax, and the prospects for improved immunodiagnostics in TB. Professor Lalvani is a superstar in this field and has contributed greatly to the TB special edition of Thorax. He is the chair of infectious diseases, co-chairman of the Section of Respiratory Infection of the National Heart and Lung Institute, and honorary consultant physician at Imperial College London and Imperial College Healthcare NHS Trust, St Maryrsquo;s Campus. He is a Wellcome Trust senior clinical research fellow and NIHR senior investigator.