Learning With Lowell show

Learning With Lowell

Summary: Discover scientists and people - who you typically won't see in mainstream headlines - who are working every day to increase each of our health spans, fight diseases, and build a better world. In this show, I will interview world-class scientists, startup founders, CEOs, and science authors covering who they are, what they are working on, and what you can do to be doing the same. You'll hear laughs, passion, and a side of science you don't normally get. Stay tuned every Tuesday for new episodes!

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Podcasts:

 Pain Management in Practice with Board Certified Dr. Mahmud M. Ibrahim | File Type: audio/mpeg | Duration: 1:01:54

Double Board Certified, Sports Medicine, Physical Medicine & Rehabilitation, Interventional Pain Management After graduating from NYU School of Medicine, he went on to complete his residency training in Physical Medicine and Rehabilitation at the Mount Sinai School of Medicine in New York. He then stayed on at Mount Sinai to complete a subspecialty in an ACGME-accredited fellowship that allowed him to subspecialize in Sports Medicine and Interventional Spine. Dr. Ibrahim is double-board certified in Physical Medicine and Rehabilitation as well as in Sports Medicine. Dr. Ibrahim was trained to perform a number of different fluoroscopic guided interventional pain management procedures. These include, but are not limited to: cervical, thoracic, lumbar epidurals, facet joint injections, sacroiliac joint injections, radiofrequency ablation, and spinal cord stimulation. He also uses ultrasound in order to diagnose and treat many common tendon, ligament, and nerve problems. His clinical interests include: musculoskeletal medicine, non-operative spine procedures, orthopedics, sports medicine, electrodiagnostic medicine, and regenerative therapy. Dr. Ibrahim has published several articles on musculoskeletal medicine. He is also a contributing author in a textbook on how to perform ultrasound guided injections. Dr. Ibrahim has provided sideline coverage at football games, captained the medical tents at the NYC marathon, and was a ringside physician for the Golden Gloves Boxing tournament. Dr. Ibrahim’s goal is to restore function, reduce pain, and promote an active, healthy lifestyle using conservative measures whenever possible. Link to website Loading…

 Path to Reviving and Restoring Species with Program Manager Bridget Baumgartner | File Type: audio/mpeg | Duration: 1:06:52

“I am a molecular biologist with research experience in several fields and disciplines. I am enthusiastic about mywork and enjoy taking creative approaches to solving big problems.” OUR MISSION (see more on their website) Revive & Restore seeks to enhance biodiversity through new techniques of genetic rescue for endangered and extinct species. We work with the world’s leading molecular biologists, conservation biologists, and conservation organizations to develop pioneering, proof-of-concept genetic rescue projects using cutting-edge genomic technologies to solve problems posed by inbreeding, exotic diseases, climate change, and destructive invasive species. GENETIC RESCUE Revive & Restore uses an expansive definition of the concept of genetic rescue to include genetic-based tools to document biodiversity, inform conventional management practices, and in some cases, enable novel genomic interventions. Genomic technology has the potential to advance and complement conventional conservation management. Most conservation focused genetic approaches have been limited to assessing very basic evolutionary processes such as gene flow, neutral genetic diversity, and effective population size, with little meaningful understanding of how genetic variation relates specifically to adaptation. Given the affordability of sequencing and the increasing prevalence of conservation threats potentially suited to genetic approaches, there is an opportunity to advance a suite of innovative new tools. Links https://www.linkedin.com/in/blbaumgartner/ Home

 DARPA Securing Food Supply Strategies with Program Manager Dr. Blake Bextine | File Type: audio/mpeg | Duration: 55:09

DARPA, program manager, Biological Technologies Office (BTO), Insect Allies, Advanced Plant Technologies (APT), Bio-complexity,Bio-systems,Disease, Syn-Bio, Engineered Living Materials (ELM) Leave Review and nomintion information https://www.podcastawards.com/ https://www.webbyawards.com/winners/ http://www.academyofpodcasters.com/ About Dr. Blake “Dr. Blake Bextine joined DARPA as a Program Manager in March 2016. He is interested in novel approaches to addressing issues facing agricultural biotechnology and biosecurity, including nucleic acid-based anti-pathogen/anti-pest strategies, insect and plant transformation strategies for rapid trait selection, and innovative approaches for altering insect behaviors. Dr. Bextine came to DARPA from the University of Texas at Tyler where he was a Professor of Biology and Assistant Vice President for Research and Technology Transfer. Prior to his arrival at UT Tyler, Dr. Bextine was a post-doctoral fellow in the Department of Entomology at the University of California, Riverside. He received his Doctor of Philosophy degree from Oklahoma State University, Master of Science in Entomology from Texas Tech University, and Bachelor of Arts in Biology from the University of Northern Iowa. Dr. Bextine is a recipient of the University of Texas System Regents’ Outstanding Teaching Award and has also won the UT Tyler President’s Scholarly Achievement Award, White Fellowship for Teaching Excellence Award, and multiple UT Tyler Researcher of the Year Awards. He received the 2014 USDA Partnership Award along with other members of the Zebra Chip Research group. In 2014, he appeared on the Discovery Channel Television Show “Tethered.”” Source Programs (as seen on darpa website) Engineered Living Materials (ELM) The goal of the Engineered Living Materials (ELM) program is to develop living materials that combine the structural properties of traditional building materials with attributes of living systems, including the ability to rapidly grow, self-repair, and adapt to the environment. Living materials represent a new opportunity to leverage engineered biology to solve existing problems associated with the construction and maintenance of our built environments, as well as new capabilities to craft smart infrastructure that dynamically responds to the surroundings. Advanced Plant Technologies (APT) The Advanced Plant Technologies (APT) program seeks to develop plants capable of serving as next-generation, persistent, ground-based sensor technologies to protect deployed troops and the homeland by detecting and reporting on chemical, biological, radiological, nuclear, and explosive (CBRNE) threats. Such biological sensors would be effectively energy-independent, increasing their potential for wide distribution, while reducing risks associated with deployment and maintenance of traditional sensors. These technologies could also potentially support humanitarian operations by, for example, detecting unexploded ordnance in post-conflict settings. Insect Allies The Insect Allies program is pursuing scalable, readily deployable, and generalizable countermeasures against potential natural and engineered threats to the food supply with the goals of preserving the U.S. crop system. National security can be quickly jeopardized by naturally occurr...

 Future of Spirulina, Questions without Answers, and Hour Discussion with CEO and Founder Elliot Roth (Part 2) | File Type: audio/mpeg | Duration: 1:05:28

Blue man group, agriculture, feeding the world, algae, Egyptian stages of death, finding a fulfilling purpose in life, 100 day challenges, value of building in LA, how he got started and has been developing his company, book and resource recommendations, hiring people, FBI bioterrorism, and much much much more in this 2 hour interview with this weeks guest Elliot Roth CEO of Spira. This episode is one you won’t want to miss! About Elliot “Elliot is incredibly motivated to solve physiological needs using simple biological design. After being trained as a University Innovation Fellow at the Stanford d.School, Elliot started multiple entrepreneurial projects including the DIYbio lab Indie Lab, TEDxVCU, and 6 failed startups. He graduated Virginia Commonwealth University with a degree in Biomedical Engineering and spent five years consulting in product design and business strategy before starting Spira. He is a Kairos Fellow, a Seasteading Ambassador, a member of the TFF NextGen Council, and sits on the Virginia Governor’s Council for Youth Entrepreneurship. Elliot has spoken at Synbiobeta, SXSW, and Thought for Food on social impact, synthetic biology and food.” Linkedin About Spira “Unless you’ve been living under a rock… It’s becoming more apparent why we need to act now. These ingredients provide the proper nutrients that people need to thrive with the consideration of how we can help the environment thrive, too. ‍ With less resources needed to grow our ingredients and a drastically increasing global population, we’re thinking multiple decades ahead.” Source Products “Spirulina Powder It takes a lot of care to build strong relationships with farmers to get the very best spirulina from the start. No heavy metals, pesticides or contaminants. ‍ Our farmers provide a consistent supply with consistent taste and consistent affordability. Did we mention its consistent? Electric Sky™ A beautiful natural blue dye unlike anything else found in nature. This spirulina extract not only gives off a mesmerizing look when added to any food, but also contains healthy antioxidant properties. Learn about the benefits and how our technology maintains this majestic hue. Spirulina Protein Isolate The world needs new plant-powered protein. The issue is that most of it tastes like s*** or is difficult to use. We’ve been working on something better.” Source Links His Linkedin Company website Company Linkedin

 Growing Spirulina, Yourself, and 100 Day Challenges with CEO and Founder Elliot Roth (Part 1) | File Type: audio/mpeg | Duration: 1:04:47

Blue man group, agriculture, feeding the world, algae, Egyptian stages of death, finding a fulfilling purpose in life, 100 day challenges, value of building in LA, how he got started and has been developing his company, book and resource recommendations, hiring people, FBI bioterrorism, and much much much more in this 2 hour interview with this weeks guest Elliot Roth CEO of Spira. This episode is one you won’t want to miss! About Elliot “Elliot is incredibly motivated to solve physiological needs using simple biological design. After being trained as a University Innovation Fellow at the Stanford d.School, Elliot started multiple entrepreneurial projects including the DIYbio lab Indie Lab, TEDxVCU, and 6 failed startups. He graduated Virginia Commonwealth University with a degree in Biomedical Engineering and spent five years consulting in product design and business strategy before starting Spira. He is a Kairos Fellow, a Seasteading Ambassador, a member of the TFF NextGen Council, and sits on the Virginia Governor’s Council for Youth Entrepreneurship. Elliot has spoken at Synbiobeta, SXSW, and Thought for Food on social impact, synthetic biology and food.” Linkedin About Spira “Unless you’ve been living under a rock… It’s becoming more apparent why we need to act now. These ingredients provide the proper nutrients that people need to thrive with the consideration of how we can help the environment thrive, too. ‍ With less resources needed to grow our ingredients and a drastically increasing global population, we’re thinking multiple decades ahead.” Source Products “Spirulina Powder It takes a lot of care to build strong relationships with farmers to get the very best spirulina from the start. No heavy metals, pesticides or contaminants. ‍ Our farmers provide a consistent supply with consistent taste and consistent affordability. Did we mention its consistent? Electric Sky™ A beautiful natural blue dye unlike anything else found in nature. This spirulina extract not only gives off a mesmerizing look when added to any food, but also contains healthy antioxidant properties. Learn about the benefits and how our technology maintains this majestic hue. Spirulina Protein Isolate The world needs new plant-powered protein. The issue is that most of it tastes like s*** or is difficult to use. We’ve been working on something better.” Source Links His Linkedin Company website Company Linkedin

 Building A Gas Station in Space with Daniel Faber CEO of Orbit Fab | File Type: audio/mpeg | Duration: 1:17:34

“Orbit Fab envisions a thriving in-space market for products and services that support both existing space businesses (communications and Earth observation) and new industries like space tourism, manufacturing, and mining. We offer a ubiquitous supply of satellite propellant in Earth Orbit, expanding the operational potential of new and existing space assets and enabling unprecedented business model flexibility for satellite owners. The future for satellites is no longer restricted to the fuel they are launched with. We provide the fuel that satellites need, where and when they need it, to achieve things never before thought possible.” source Livestream CEO Daniel Faber “A serial entrepreneur leading a number of startups in Silicon Valley, Daniel Faber has leveraged his experience in a wide range of industry sectors to bring together teams and build companies in the emerging field of in-space operations. As the former CEO of Deep Space Industries, Mr. Faber built a solid technology business, aggressively advancing a vision of delivering off-earth resources to the space economy. Under his leadership, the company released its first products with significant customer traction, grew sales from zero to nearly $10 million, changed global perceptions and regulations around space resources, and positioned DSI to systematically create and commercialize all the technology necessary for mining asteroids. As a serial entrepreneur in the aerospace and mining industries prior to DSI, Mr. Faber has grown several high tech companies from startup through to commercial success. He is the recipient of multiple innovation awards and has filed a number patents in the fields of mining, entertainment, medical imaging, and aerospace. Mr. Faber is in the process of completing a double-MBA at UCLA Anderson and National University Singapore (NUS), he holds a degree in engineering from the University of New South Wales and a Postgraduate Certificate in Antarctic Studies from the University of Canterbury. He has served as a director and officer in several non-governmental organizations. ” Source Orbit Fab Products RAPIDLY ATTACHABLE FUEL TRANSFER INTERFACE (RAFTI) Fill and Drain The Rapidly Attachable Fluid Transfer Interface (RAFTI) provides cost effective, reliable satellite fill and drain functions during ground operations. The service valve side is low profile, comparable to existing solutions. The rugged latching mechanism and triple seal design ensures a safe propellant transfer. RAFTI is designed for ease of use while exceeding industry range safety requirements. Redundant data logging allows for remote monitoring. On Orbit Refueling RAFTI is designed to allow reliable propellant transfers in the harshest space environments, making it ideal for mission operations at any orbit. High and low pressure variants are compatible with common modern propellants and pressurants with external leakages less than 1×10-6 scc/s. RAFTI is configurable to be normally-open or normally-closed in case of power loss, allowing for fail-safe and safe-fail operations for any mission profile. Docking RAFTI supports both primary docking or secondary attachment of two spacecraft. The double action latch mechanism accommodates significant misalignment on all axes during the docking process, allowing for self aligning operations without the need for complex robotic arms. High clamping force accommodates high pressure fluid connections and satellite body movements. Improved reliability by minimizing sliding surfaces and avoiding motors or gears RIGID TANKER ISS PROTOTYPE (GEN-0) – EST.

 Longevity, Senescence, & Building a Therapeutic startup with Dr. Moody CEO Ichor Therapeutics | File Type: audio/mpeg | Duration: 25:17

“Dr. Moody is a process-oriented drug developer and executive who has specialized in the study of aging and aging mechanisms for over a decade. Since 2013, Dr. Moody has successfully built Ichor Therapeutics from a living room start-up into a premier, vertically integrated research organization focused on drug discovery and development for pathways of aging. R&D initiatives that constitute Ichor’s portfolio companies span enzyme therapy (Lysoclear, Inc.), senolytics (FoxBio, Inc.), small molecule drug discovery (Antoxerene, Inc.), antibody mimetics (Auctus Biologics, Inc.), protein chemistry tools (RecombiPure, Inc.), contract research services (Icaria Life Sciences, Inc.) and a strategic investment fund (Grapeseed.Bio). Dr. Moody has received graduate-level training in medicine, business, and laboratory research. ” Source Ichor Therapeutics A vertically integrated pre-clinical contract research organization that broadly focuses on the study of aging and aging pathways. The company offers a number of services and programs to support its clients and strategic priorities. Ichor operates from its corporate offices and research laboratories in rural LaFayette, NY (just south of Syracuse). The company is eager to engage collaborators and clients in industry and academia who share its vision of delivering next generation therapies for the illnesses of aging. Dr. Kelsey Moody “Dr. Moody is a process-oriented drug developer and executive who has specialized in the study of aging and aging mechanisms for over a decade. Since 2013, Dr. Moody has successfully built Ichor Therapeutics from a living room start-up into a premier, vertically integrated research organization focused on drug discovery and development for pathways of aging. R&D initiatives that constitute Ichor’s portfolio companies span enzyme therapy (Lysoclear, Inc.), senolytics (FoxBio, Inc.), small molecule drug discovery (Antoxerene, Inc.), antibody mimetics (Auctus Biologics, Inc.), protein chemistry tools (RecombiPure, Inc.), contract research services (Icaria Life Sciences, Inc.) and a strategic investment fund (Grapeseed.Bio). Dr. Moody has received graduate-level training in medicine, business, and laboratory research. ” Source “Business units: (1) enzyme therapy (Lysoclear, Inc.), (2) senolytics (FoxBio, Inc.), (3) small molecule drug discovery (Antoxerene, Inc.), (4) antibody mimetics (Auctus Biologics, Inc.), (5) protein chemistry tools (RecombiPure, Inc.), (6) contract research services (Icaria Life Sciences, Inc.), and (7) a strategic investment fund (Grapeseed.Bio) Responsibilities: Raised >$20M in funding to grow company from living room start-up to GXP facility with >40 employees. Designed and supervised buildout of four wet lab facilities (current facilities ~13,000 ft2 including SPF vivariums suitable for SCID work). Managed client relations, investor relations, and operating budgets >$7M. Built and worked with interdisciplinary teams to set translational plans for portfolio companies. Implemented GXP processes. Designed and executed numerous sponsored research projects. Managed collaborations with 3rd party companies, foundations, and academic institutions. Negotiated contracts with clients and licensing agreements with foundations and universities. Mentored and incubated visiting scientists and other start-up companies. Served on several advisory boards for companies, universities, non-profits, and investment funds” Source Links His Linkedin Company Linkedin

 Anti-Aging, Mitochondria DNA, Obstacles, Next Generation Doping, Controversies, and Leigh Syndrome with Dr.Matthew O’Connor | File Type: audio/mpeg | Duration: 29:28

The next part in a series I’ve been doing on anti-aging researchers and research. The George Church and Nichola Conlon episodes already up. In this episode focuses on Mitochondria – we get into hurtles and problems with Mitochondria, next generation doping with Mitochondria , Leigh Syndrome (Mitochondria disease), allotopic expression. and more in under 30 minutes. Dr. Matthew O’Connor Vice President of Research “Matthew was awarded his Master’s degree at Northwestern Medical in 1999 for his work studying behavioral neuroscience in aged rodents. In 2005, at Baylor College of Medicine he received a PhD in Biochemistry for his work on proteins that regulate human telomeres. Postdoctoral research includes work at UC Berkeley on muscle stem cells and aging. Since 2010, Dr. O’Connor has headed up the MitoSENS project at the research center in Mountain View, California. His research is focused on “allotopic expression” of mitochondrial genes where his team is engineering mitochondrial genes to be expressed from the nucleus and targeted to the mitochondia. Since 2012 Dr. O’Connor has had broad oversight over many areas of research at SRF. Matthew O’Connor is passionate about performing basic research to combat the diseases and disabilities of aging.” Source SENS “SENS Research Foundation (SRF) is a 501(c)3 non-profit organization focused on transforming the way the world researches and treats age-related disease. SRF focuses on a damage repair paradigm for treating the diseases of aging, which it advances through scientific research, advocacy and education. SENS Research Foundation supports research projects at universities and institutes around the world with the goal of curing such age-related diseases as macular degeneration, heart disease, cancer, and Alzheimer’s disease. Educating the public about how we can solve the economic and political issues stemming from an aging world population and training researchers to support a growing regenerative medicine field are also major endeavors of the organization that are being accomplished though advocacy campaigns and educational programs.” Links SENS MITOSENS project Education options Twitter SENS Facebook SENS SENS Linkedin SENS Youtube Key terms from episode * Phineas Gage * Leigh syndrome  * mitochondria * MT-ATP8 gene * MT-ATP6 gene * genetic engineering * gene therapy * Nuclear DNA (nDNA), or nuclear deoxyribonucleic acid * Nuclear genome * assays * molecular biology * RNA * Proteins * antigen * electron transportation train * allotopic expression * Free Radical DNA danger * CRISPR * Bodybuilding * Next generation doping

 SpaceBase, Democratizing Space, Building Space entrepreneurship in New Zealand with Emeline Paat-Dahlstrom | File Type: audio/mpeg | Duration: 50:48

“The best way to predict the future is to create it”  Abraham Lincoln, Peter Drucker, and Emeline Paat-Dahlstrom About her in her own words “Space entrepreneur, global change maker, and aspiring exponential innovator. Emeline is a Co-Founder at SpaceBase, a social enterprise focused on democratizing space for everyone by co-creating space ecosystems in emerging countries, starting with New Zealand. Emeline is also on the faculty of Singularity University and a Co-Founder of International Space Consultants both based in California, USA. In 2017, she joined the inaugural cohort of the Edmund Hillary Fellowship program in New Zealand. She is an international traveler, adventure seeker, outdoor enthusiast, and aspiring environmentalist. Originally from the Philippines, she has visited over 80 countries and territories, and has lived/worked in the Philippines, France, Switzerland, Canada, US, Spain, Sweden, Austria, China, and now New Zealand. Emeline was most recently on the executive management team of Singularity University (SU) as the Chief Impact Officer and previously the EVP of Operations for five years. Her role was to oversee the implementation of SU’s mission and to maximize impact in all of SU’s programs and initiatives. Emeline also served as Space track lead for SU’s 10 week Global Solutions Program for the past four years. Emeline has a BS in Physics from the University of the Philippines and a MS in Earth and Space Science from York University, Canada. She attended the International Space University (ISU) Space Studies Program in Strasbourg, France and subsequently worked and volunteered for ISU developing and running graduate academic operations across two decades. In commercial space development, she has worked and consulted for several startups including serving as Director of Program Development and Research, and Director of Operations for Space Adventures Ltd, a space tourism company sending private citizens to the International Space Station; and Odyssey Moon and Moon Express, which plan commercial transport to the Moon. Emeline is co-author of the book “Realizing Tomorrow: The Path to Private Space Flight,” University of Nebraska Press (2013), which was selected that year for the US Air Force’s Chief of Staff Reading List. ” International Space Consultants Space consulting Partnership specializing in proposal coordination, research analysis, and program and project management. Clients: Lockheed Martin, Raytheon, Keane, International Space University, Space Adventures, Optech Canada, Odyssey Moon Limited, CSI, TGV Rockets. Worked on a book (Realizing Tomorrow: The Path to Private Spaceflight) for University of Nebraska Press. Formerly PFO Manager for Odyssey Moon Limited. SpaceBase NZ “SpaceBase is a social enterprise founded by three Edmund Hillary Fellows with deep knowledge and connections into the global space industry – Emeline Paat-Dahlstrom, Eric Dahlstrom and Rich Bodo. SpaceBase is creating an online collaborative platform to support entrepreneurs in emerging space industries – providing access to training, networking, technical services, and investment opportunities.” Edmund Hillary Fellowship “The Edmund Hillary Fellowship offers a once-in-a-lifetime opportunity for visionary entrepreneurs, investors and startup teams to live and work in New Zealand and to create scalable, positive global impact. Launching in early 2017, up to 100 international and 20 New Zealand-based Fellows will be selected each year to join the three-year programme, and become part of a diverse community of exceptional entrepreneurs and investors. International candidates accepted into EHF can apply for a Global Impact Visa,

 Life with San (Bushmen), Nature Focused Life, and Expanding Your Mind with Best Selling Author Elizabeth Marshall Thomas | File Type: audio/mpeg | Duration: 51:07

Elizabeth Thomas has lead an amazing life, authoring countless priceless books, visiting many places on the planet, and being a part of many fascinating discoveries. Now she is sharing her experiences with the world through this podcast. You will hear what it was like to live with the San, her experiences with nature, how to challenge yourself to appreciate nature more, and other amazing stories. Seriously, you don’t want to miss this episode! About Elizabeth Marshall Thomas “Elizabeth Marshall Thomas has spent a lifetime observing other creatures and other cultures from here own backyard to the African Savannah. Her books have transported millions into the hidden lives of animals. She’s chronicled the daily lives of African tribes, and even imagined the lives of prehistoric humans. Now, she opens the doors to her own.” Source   Sample of her life (Read more on her website) The Harmless People “Between 1950 and 1956 Elizabeth Marshall Thomas accompanied three expeditions to visit the Bushman hunter-gatherers of South-West Africa (now Namibia) and Bechuanaland (now Botswana). At that time the Bushmen were the last significant population who still lived by hunting and gathering, the economy practiced by all human beings and the ancestors of human beings for millions of years. Few firsthand accounts of hunter-gatherer life were written before this one and because, since its publication, most Bushmen have been evicted from their former homes or chose to change their traditional way of life, this book remains one of the only few accounts of the old way of life. In 1986 and 1987. Thomas revisited the people she had known in Namibia and found them much changed.” Source Links * http://elizabethmarshallthomas.net Official Elizabeth Marshall Thomas Website * Interview with Elizabeth Marshall Thomas on Mother Nature Network * Salon.com people | Elizabeth Marshall Thomas * Socializing Humans Other interview you’ll like, if you enjoyed this one Wolf Nation, Nature Writing, Exploring the love of Nature, and More with Author Brenda Peterson Amazing nature author Brenda Peterson (Wild Orca, Wolf Nation, and Catastrophe by the Sea) talks about her love of nature, getting into writing, finding the kernel of your memoir, wolfs, and much more in this Learning with Lowell interview with your host Lowell Thompson,Check this one out!   Best-Selling Science Author, Sy Montgomery, Discusses Writing 20+ books, Nature, Favorite Unwritten Stories, and Future Goals Bestselling science author Sy takes time out of her busy day and travels to talk about her latest book, life as a science writer, nature, advice for new writers, and much more. I love her books, and if you give this episode a try, you’re going to want to read her books too! Try not to love and be inspired by all that Sy has done and written about! Book recommendations The Hidden Life of Life A Walk through the Reaches of Time

 Plant Natural Products, Folk Medicine, and biosynthesis of Molecules with Dr. Sarah O’Connor | File Type: audio/mpeg | Duration: 48:08

Sarah’s research focuses on elucidating biochemical pathways in plants including those involved in the synthesis of the monoterpenes and the alkaloids, the enzymes involved and the evolution of these pathways. Learning with Lowell Welcome today to the learning with Lowell science podcast with your host Lowell Thompson. This podcast was created after I met the doctors that made the drug that would eventually save my life. At that time I was working 2 jobs, going to college full time, and was in and out of the ICU and ER. After I left college I worked 12-16 hour days to pay off my medical and college debt. Many of you work equally, if not longer hours, and don’t have time to current with latest news, develop mentors, and get advice. With this podcast you will see the new technology, advice on how to get into their fields and to learn more, and if I’m doing my job right you can tease out strategies, tactics, and more to use in your every day life. All while enjoying fun long form conversations. This podcast was inspired by the Joe Rogan, Tim Ferriss, and Neil deGrasse Tyson shows. About Sarah O’Connor and Her Lab (Source) “Sarah’s research focuses on elucidating biochemical pathways in plants including those involved in the synthesis of the monoterpenes and the alkaloids, the enzymes involved and the evolution of these pathways. Sarah works on plants in the mint family (Lamiaceae) and uses modern sequencing and bioinformatics to characterise pathways and identify new genes. This work has led to the development of platforms which allow fast, inexpensive production of compounds. * Monoterpene and alkaloid synthesis * Evolution of biochemical pathways in plants * Synthetic biology for compound production Plants produce hundreds of thousands of complex metabolites called “natural products” that have many uses. Anti-cancer agents such as vinblastine and taxol, the analgesic morphine, and the anti-malarials artemisinin and quinine are each natural products that are produced by a plant. Despite the importance of these compounds, it is unclear how many of these complicated molecules are made by the plant. The O’Connor group elucidates and engineers the metabolic pathways that construct these compounds from simple building blocks. An understanding of these pathways allows us to harness the wealth of compounds and biocatalysts that plants have provided. Moreover, the group can also begin to speculate how and why plants evolved to produce some of these molecules. They take a multi-disciplinary approach to answering research questions, using plant molecular biology, enzymology and chemical strategies in their group.” Awards (from Wiki) * 2019 – Royal Society of Chemistry Perkin Prize for Organic Chemistry[4] * 2018 – European Research Council (ERC) Advanced Grant * 2017 – Elected to European Molecular Biology Organization[5] * 2013 – 

 Engineered Living Materials, Bio-films, and How to get into ELMs with Expert Dr. Peter Nguyen of the Wyss Institute | File Type: audio/mpeg | Duration: 1:04:46

Growing the materials of the future with living organisms sounds like science fiction, but it’s already science fact, and in this episode you learn about the history of Engineered Living Materials, their strengths and weaknesses, where they need development, and the thoughts and passions of one of the leading experts in this burgeoning field! This is an episode you don’t want to miss. About Peter (From Linkedin) How can we leverage the incredible complex functionalities of biological systems and integrate them into smart materials? Could we integrate shelf-stable cell-free technology into everyday materials to create biological computing materials? Or perhaps harness the self-assembling and autonomous properties of living systems to turn them into smart micro-scale factories for producing advanced materials? Those are the questions I’m trying to answer in my current research. I’m interested in the fusion of synthetic biological and materials science approaches for engineering organic-nanomaterial systems —specifically, the reprogramming of cells into “molecular foundries” and the integration of freeze-dried cell-free systems into synthetic materials to enable novel biological smart materials. ■ In my postdoctoral work at Harvard University, I have conceived, designed, and fully developed a technology platform BIND (Biofilm-Integrated Nanofiber Display) that allows for the re-engineering of the bacterial bioflm extracellular material to have programmed artificial functions. These “Engineered Living Materials” establish living systems as biological self-replicating nanomaterials factories. ■ My other work as a Wyss Technology Development Fellow has centered on the development of freeze-dried cell-free technology to incorporate synthetic biology into various technologies and materials in a shelf-stable format. This “just-add-water” format allows complex biological circuits to be implemented in a portable, low-cost, and inexpensive manner. ■ My prior thesis work at Rice University centered on the design of synthetic protein switches that operated in hyperthermophilic organisms for detecting protein-protein interactions. ■ My other research interests include novel 3D printing materials, using biofilm-derived materials for architectural and textile technologies, phage display, synthetic cells, and developing amyloid therapeutics.   Links: Biobits video Tedtalk on on demand bio-manufacturing  Peter’s Website with research’ Wyss Institute  What was your favorite quote, lesson, or thing you learned from this episode? Let me know in the comments! Select Links and Terms from this episode * Arthur C. Clark  * Bio-containment  * Scaffold * Spore * Boston, MA * Wyss Institute * PhD Scientist * Interdisciplinary * Genetics * Genetic Engineering * Post Doc * I Gem (Therapeutic HIV) * Citizen science * Bio labs * Bio hacking

 Wolf Nation, Nature Writing, Exploring the love of Nature, and More with Author Brenda Peterson | File Type: audio/mpeg | Duration: 1:10:53

Amazing nature author of 17+ books Brenda Peterson (Wild Orca, Wolf Nation, and Catastrophe by the Sea) talks about her love of nature, getting into writing, finding the kernel of your memoir, wolfs, and much more in this Learning with Lowell interview with your host Lowell Thompson,Check this one out! About Brenda Peterson (As seen on her website) Through her work as a novelist and nature writer, Peterson’s curiosity about and respect for nature radiates through her 17 books, which range from her first memoir Build Me an Ark: A Life with Animals, chosen as a “Best Spiritual Book of 2001,” to three novels, one of which, Duck and Cover, was chosen by New York Times as Notable Book of the Year. Her new memoir, I Want To Be Left Behind: Finding Rapture Here on Earth was selected by The Christian Science Monitor among the Top Ten Best Non-Fiction Books of 2010. Her novels include Animal Heart (Sierra Club Books) and River of Light (Knopf), as well as Becoming the Enemy (Graywolf Press). Her nonfiction books include Living by Water and the National Geographic book Sightings: The Gray Whale’s Mysterious Journey. These works established Peterson as a prominent creative nonfiction writer, extensively profiled in the reference work America’s Nature Writers. Peterson’s bestselling anthology Intimate Nature: The Bond Between Women and Animals is often taught in university courses. Her nonfiction has appeared in numerous national newspapers, journals, and magazines, including The New York Times, Chicago Tribune, San Francisco Chronicle, Reader’s Digest, Christian Science Monitor, O: The Oprah Magazine, and Utne Reader. Peterson lives in Seattle. For the past two decades, she has studied and written about animals, especially marine mammals and wolves. She is the founder of the Seattle-based grassroots conservation group Seal Sitters. Since 1993 she has contributed environmental commentary to NPR and is a frequent commentator to The Huffington Post. See her blog and website for online links. Her new picture book, Leopard and Silkie: One Boy’s Quest to Save the Seal Pups, was published by Henry Holt for Young Readers and was a 2013 winner of National Science Teacher’s Association “Outstanding Science Books for K-12.” Her new novel, The Drowning World, part of her fantasy/sci-fi Aquantis Series begun with Animal Heart, is just out in ebook and paperback from Ingram and Espresso Book Machine Network. Peterson’s new natural history book, WOLF NATION, is out from Merloyd Lawrence Books and receiving excellent reviews. Forbes magazine selected it as a Best Conservation Book of the Year. The new picture books are WILD ORCA: The Oldest, Wisest Whale in the World (Christy Ottaviano Books/Macmillan) chosen by the National Science Teachers Assciation as an Outstanding Science Book for K-12 and a Junior Library selection. LOBOS: A Wolf Family Returns to the Wild(Sasquatch Press) has just been long-listed for the GREEN EARTH BOOK AWARD. And the forthcoming Catastrophe by the Sea is due out on September 24th, 2019 from West Margin Press. Read more about Peterson’s memoir: Brenda’s Linked in profile: https://www.linkedin.com/profile/view?id=82471851&trk=hb_tab_pro_top More on Leopard and Silkie at the book’s website: http://www.leopardandsilkie.com For more on WILD ORCA: http://www.brendapetersonbooks.com/wild-orca/ For more on LOBOS: http://www.brendapetersonbooks.com/intimate-nature/  For more on Catastrophe by the Sea: http://www.brendapetersonbooks.com/face-to-face/ To see all of the Delphinius books please visit...

 Dr. Arturo Casadevall of John Hopkins Bloomberg School of Public Health Discusses Fungi | File Type: video/mp4 | Duration: Unknown

Fungi, radiation shielding, and current microbiology research are just a few of the topics we get into on this episode of the Learning with Lowell science, biotech, and space podcast. Fortunately for you all Dr. Arturo has a wiki page which I will cite below. “Arturo Casadevall is a Bloomberg Distinguished Professor[1] of Molecular Microbiology & Immunology and Infectious Diseases at the Johns Hopkins Bloomberg School of Public Health and Johns Hopkins School of Medicine, and the Alfred and Jill Sommer Professor and Chair of the W. Harry Feinstone Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health.[2] He is an internationally recognized expert in infectious disease research, with a focus on fungal and bacterial pathogenesis and basic immunology of antibody structure-function. Biography Arturo Casadevall was born in Sancti Spíritus, Cuba in 1957. He moved to Elmhurst, Queens, New York City in 1968 and became a U.S. citizen in 1976. Casadevall received his Bachelor of Arts degree in Chemistry from Queens College, City University of New York in 1979, and his M.S. and Ph.D in Biochemistry from New York University in 1983 and 1984.[3] He then received his M.D. from New York University...

 Sean C. Casey Space Business Development and Principal Space Investor Expert | File Type: audio/mpeg | Duration: 28:21

How he says no, ways to get into the space industry, what do space startups need to focus on, why getting to the top 3% should be your goal, overlooked space markets, atlas space business development, how to do market research, and where he could use help.   VP of Commercial business development at Atlas Space Operations “As the VP for commercial business development, my intent is to serve the global spaceentrepreneur market in meeting corporate spaceflight communication needs, technologydemonstration milestones, and customer/investor expectations through an innovative suite oftimely, reliable, and cost effective ATLAS products and services.” Linkedin  About Atlast Space Operations “ATLAS Space Operations, Inc. provides a revolutionary approach to satellite communications and in 2017 was listed by Morgan Stanley as a top 12 disruptor in the satellite industry – by providing satcom as a service. ATLAS was founded on the ideal of providing affordable access to space for all. We believe that providing an exceptional level of service shouldn’t be cost prohibitive. Stemming from the innovation in the satellite and launch sectors, there became a data bottleneck on the ground – with no solution in sight. Enter ATLAS. Unlike legacy ground solutions, ATLAS utilizes a software-centric, cloud-based approach – the Freedom™ Software Platform. This proprietary software allows us to cut costly overhead, streamline operations and allow customers to gather more data, faster from space for use in the real world. We developed an ever-growing ground network of antenna designed to cover more of the globe without increasing costs to the customer. Built around the Freedom™ Software Platform, our network provides a simple, affordable, scalable option for satellite operators and launch companies alike. From spacecraft, to antenna, to your customer – our simplified approach supplies the data you need, when you need it. Get started doing what you do best – build your satellite. Let us worry about the rest. For more information visit www.atlasground.com and follow us on Twitter at @AtlasSpace” Link Website: https://www.atlasground.com/ Twitter: at @AtlasSpace Principal at NewCap Partners Investment banking M&A for the NewSpace sector. Pending Series 79 license. Link About NewCap Partners “NewCap Partners was founded in 1987 to bring high quality investment banking services to private companies in Southern California. Since its inception it has grown both in terms of its professional staff and as well the geographic span of it activities. From a single office in Los Angeles, we now have offices in Orange County and Silicon Valley. We work with business owners, boards, shareholders and management teams to develop and execute on financial transactions and implement strategies to maximize shareholder value. Our senior investment bankers have experience dealing with both public and private companies in a variety of industries. The industry expertise of our bankers is complemented by independent industry consultants who provide us with contacts and insights into a variety of industries. Over the last 25 years, we have completed a variety of transactions including buy-side M&A, sell-side M&A, debt financings, equity financings, joint ventures, licensing transactions, valuations and fairness opinions.” Link Linkedin: https://www.linkedin.com/company/newcap-partners/about/

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