DTB podcast show

DTB podcast

Summary: For 50 years, Drug and Therapeutics Bulletin (DTB) has provided rigorous and independent evaluations of, and practical advice on, individual treatments and the overall management of disease for doctors, pharmacists and other healthcare professionals. DTB has always been wholly independent of the pharmaceutical industry, Government and regulatory authorities. DTB is also free of advertising and other forms of commercial sponsorship. * The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Podcasts:

 Deprescribing in the time of COVID-19 | File Type: audio/mpeg | Duration: 21:36

With the coronavirus pandemic restrictions still in place, this socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor), who provide an overview of the June issue of DTB. This includes an editorial that discusses whether clinicians should be deprescribing some medicines during the pandemic, and a summary of the EMA's advice on the use of drugs that affect the renin-angiotensin system in people who have COVID-19. The main article looks at the gastrointestinal risks of NSAIDs and the evidence for gastroprotection, and the issue finishes with a case report of drug reaction with eosinophilia and systemic symptoms syndrome in a patient taking lamotrigine. Please read the full issue: https://dtb.bmj.com/content/58/6. Subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

 Improving consultations with children and adolescents, plus treating Covid-19 with ibuprofen | File Type: audio/mpeg | Duration: 4:53

As the UK continues to be in lockdown because of the coronavirus pandemic, this podcast only features David Phizackerley, DTB's Deputy Editor, who provides a brief overview of the May issue of DTB. This includes an editorial that discusses the challenges facing clinicians in involving children and young people in decisions about their healthcare; a summary of the EMA's advice on the use of ibuprofen in people who have Covid-19; and an article on the development of shared care prescribing guidelines over the last 30 years. The main article looks at the benefits and harms of using potassium permanganate for wound care, and the issue finishes with a case report of hypersensitivity pneumonitis associated with sertraline. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (podcasts.apple.com/gb/podcast/dtb-…ast/id307773309). Thank you for listening. Go well and stay well.

 April 2020 - Lung volume in COPD: when less is more | File Type: audio/mpeg | Duration: 14:39

In April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss lung volume reduction surgery for patients with emphysema-predominant COPD (https://dtb.bmj.com/content/58/4/50). They highlight the results of a trial of low-dose amitriptyline for chronic low back pain (https://dtb.bmj.com/content/58/4/53), discuss the use of depot triamcinolone injection for hay fever (https://dtb.bmj.com/content/58/4/57), and talk about a case in which dapagliflozin was thought to have caused euglycaemic diabetic ketoacidosis (https://dtb.bmj.com/content/58/4/60). If you enjoy the DTB podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Read the full April issue: dtb.bmj.com/content/58/4

 March 2020 - Dapagliflozin for type 1 diabetes: ensuring benefits outweigh the risks | File Type: audio/mpeg | Duration: 10:10

In March's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the decision to extend the license for dapagliflozin 5 mg tablets to include use by people with type 1 diabetes and highlight concerns over the incidence of diabetic ketoacidosis. They review an article on managing asthma before and during pregnancy and talk about a case of partial nephrogenic diabetes insipidus associated with lithium therapy. Read the full March issue: dtb.bmj.com/content/58/3 If you enjoy the podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

 February 2020 - Registering our interest | File Type: audio/mpeg | Duration: 10:05

In February's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the impact of conflicts of interest and highlight the need to establish comprehensive registers of conflicts of interest for healthcare professionals, healthcare providers and patient support groups. They briefly review an article on melatonin for jet lag (a longer version is available here: https://soundcloud.com/bmjpodcasts/melatonin-for-jet-lag?in=bmjpodcasts/sets/dtb-podcast), discuss a review of the management of nocturnal enuresis and highlight a report of a possible case of statin-induced delayed rhabdomyolysis. Read the full February issue: https://dtb.bmj.com/content/58/2 If you enjoy the podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

 Melatonin for jet lag | File Type: audio/mpeg | Duration: 8:54

In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a formulation of melatonin that has been licensed in the UK for the management of jet lag. The editors review the evidence for its effectiveness in reducing symptoms of jet lag and consider whether it should be available from the National Health Service. Read the article here: http://dx.doi.org/10.1136/dtb.2019.000074. Please subscribe to the DTB Podcast to get episodes automatically downloaded to your phone and computer every month. If you enjoy the show, please leave us a review or a comment at podcasts.apple.com/gb/podcast/dtb-…ast/id307773309. Thank you for listening!

 January 2020 - Polypharmacy and deprescribing: just ask the patient | File Type: audio/mpeg | Duration: 10:08

In January's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the burden of overprescribing and discuss how to tackle some of the barriers to deprescribing (https://dtb.bmj.com/content/58/1/2). They also review an article on the place of aspirin for primary prevention of cardiovascular disease (https://dtb.bmj.com/content/58/1/3), highlight an article on prescribing for pregnancy for women with mental health issues (https://dtb.bmj.com/content/58/1/8), and discuss a case report of sitagliptin-induced seronegative rheumatoid arthritis (https://dtb.bmj.com/content/58/1/12). Please subscribe to get episodes automatically downloaded to your phone and computer every month. If you enjoy the podcast, please leave us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

 December 2019 - Has the polypill finally proven its worth? | File Type: audio/mpeg | Duration: 10:29

In December's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the results of a recent study that assessed the effect of a combination pill containing aspirin, atorvastatin, enalapril and hydrochlorothiazide on major cardiovascular outcomes - https://dtb.bmj.com/content/57/12/178. The editors discuss prasterone, a newly introduced treatment for vulvar and vaginal atrophy - https://dtb.bmj.com/content/57/12/185. They also review a case report of retrograde ejaculation associated with quetiapine and treatment with low-dose imipramine - https://dtb.bmj.com/content/57/12/189. Read the December issue on the DTB website: https://dtb.bmj.com/content/57/12.

 November 2019 - Meeting QOF hypertension targets but failing the patient | File Type: audio/mpeg | Duration: 11:14

In November's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss whether primary care targets for managing blood pressure control in older people are achievable or desirable. The editors also introduce the first of a series of articles that consider therapeutic challenges when preparing for pregnancy and highlight some of the key issues that should be considered for all women as part of pre-pregnancy care. They also review a case report of apixaban-induced acute interstitial nephritis. Read the full November issue: https://dtb.bmj.com/content/57/11

 October 2019 -Medicines optimisation: time to review fibrates? | File Type: audio/mpeg | Duration: 8:40

In October's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss wide variation in the use of fibrates and the need for clinicians to consider whether their prescribing of fibrates is up to date and appropriate for their patients. The editors also talk about the evidence for fibrates in primary and secondary prevention of cardiovascular disease, highlight recent changes in the BNF and review a case of severe acute ocular hypertension following pulsed methylprednisolone. Read the full October issue: https://dtb.bmj.com/content/57/10

 September 2019 - Social prescribing: right idea, wrong name? | File Type: audio/mpeg | Duration: 10:38

In September's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the roll out of social prescribing across the NHS in England. The editors also talk about a new formulation of naloxone for emergency treatment of opioid overdose in adults and review a case that involved successful thrombolysis for acute ischaemic stroke after using idarucizumab to reverse the action of dabigatran etexilate. To read any of the September articles, please visit: https://dtb.bmj.com/content/57/9.

 August 2019: Time to speed up the diagnosis of pre-eclampsia | File Type: audio/mpeg | Duration: 5:48

In August's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss pre-eclampsia and the benefit of measuring the level of placental growth factor to help speed up diagnosis. The editors also talk about the challenge of communicating evidence to patients and review a case of complex encephalopathy arising from the combination of opioids and gabapentin. Read the full issue: https://dtb.bmj.com/content/57/8.

 August 2019: Time to speed up the diagnosis of pre-eclampsia | File Type: audio/mpeg | Duration: 5:48

In August's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss pre-eclampsia and the benefit of measuring the level of placental growth factor to help speed up diagnosis. The editors also talk about the challenge of communicating evidence to patients and review a case of complex encephalopathy arising from the combination of opioids and gabapentin. Read the full issue: https://dtb.bmj.com/content/57/8.

 July 2019: It is hard work being a patient | File Type: audio/mpeg | Duration: 7:19

In July's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the work that patients have to do to manage their health and how this is not recognised by clinical guidelines. The editors also talk about the non-drug management of low back pain and discuss a case of metformin-associated lactic acidosis precipitated by liraglutide use. Read the full issue: dtb.bmj.com/content/57/7.

 July 2019: It is hard work being a patient | File Type: audio/mpeg | Duration: 7:19

In July's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the work that patients have to do to manage their health and how this is not recognised by clinical guidelines. The editors also talk about the non-drug management of low back pain and discuss a case of metformin-associated lactic acidosis precipitated by liraglutide use. Read the full issue: dtb.bmj.com/content/57/7.

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