Summary: Self-isolation can be difficult. If you read any of the advice about how to best deal with isolation – which comes from astronauts, submariners and others – you will come across some of the same bits of advice. These include maintaining a routine and staying physically active. However, there is one bit of advice that is crucial but that we all find very challenging – even before the coronavirus pandemic. That is maintaining and creating a meaningful connection with others. Meet Georgie Nightingall.