Pain Pathway and Analgesics (NSAIDs, Opioids, Antidepressants, and Anticonvulsants)
Summary: Everything you need to know about pain! Well, nearly... - Pain pathways (spinothalamic) versus fine touch (dorsal column) pathway to the brain. - A delta versus C fibres - Painful stimuli (mechanical, thermal, chemical) - Brown-sequard syndrome (clinical implications) - Pain gate theory - Endogenous Opioid system (endorphin, enkephalin, dynorphin) - Non-steroidal antiinflammatory drugs (NSAIDs) (aspirin, ibuprofen, celecoxib, paracetamol) - Opiates (Morphine) - Antidepressants (Tricyclics, SSRIs, SNRIs) - Anticonvulsants (Gabapentin) - And more!!