183 -Neuropsychobiology: Dopamine, Serotonin, GABA | Addiction Counselor Certification Training




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Summary: <p>Neurobiology: Dopamine, GABA, Serotonin, Acetylcholine<br> Dr. Dawn-Elise Snipes PhD, LPC-MHSP, LMHC<br> Executive Director, AllCEUs.com</p> <p><a href="https://www.allceus.com/member/cart/index/product/id/752/c/">Counseling CEUs for this podcast can be found at https://www.allceus.com/member/cart/index/product/id/752/c/</a></p> <p>Objectives<br> ~ Define Neurobiology<br> ~ For the following neurotransmitters, Dopamine, GABA, Serotonin, Acetylcholine, identify<br> ~ Their mechanism of action/purpose<br> ~ Where they are found<br> ~ Symptoms of excess &amp; insufficiency<br> ~ Nutritional building blocks<br> ~ Medications<br> ~ Neurological changes over the lifespan<br> What is Neurobiology<br> ~ Neurobiology is the study of the brain and nervous system which generate sensation, perception, movement, learning, emotion, and many of the functions that make us human<br> Dopamine<br> ~ Mechanism of action/purpose<br> ~ Movement<br> ~ Memory<br> ~ Pleasurable reward<br> ~ Behavior and cognition<br> ~ Attention<br> ~ Sleep<br> ~ Mood<br> ~ Learning<br> Dopamine<br> ~ Mechanisms of Action<br> ~ Precursor, L-DOPA is synthesized in brain and kidneys<br> ~ Dopamine functions in several parts of the peripheral nervous system<br> ~ In blood vessels, it inhibits norepinephrine release and acts as a vasodilator (relaxation)<br> ~ In the pancreas, it reduces insulin production<br> ~ In the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa<br> ~ In the immune system, it reduces lymphocyte activity.<br> Dopamine<br> ~ Symptoms of excess<br> ~ Unnecessary movements, repetitive tics<br> ~ Psychosis<br> ~ Hypersexuality<br> ~ Nausea<br> ~ Most antipsychotic drugs are dopamine antagonists<br> ~ Dopamine antagonist drugs are also some of the most effective anti-nausea agents<br> Dopamine<br> ~ Symptoms of insufficiency<br> ~ Insufficient dopamine<br> ~ Negative symptoms of schizophrenia<br> ~ Pain<br> ~ Parkinson’s Disease<br> ~ Restless legs syndrome<br> ~ Attention deficit hyperactivity disorder (ADHD)<br> ~ Neurological symptoms that increase in frequency with age, such as decreased arm swing and increased rigidity.<br> ~ Changes in dopamine levels may also cause age-related changes in cognitive flexibility.<br> Dopamine<br> ~ Symptoms of excess &amp; insufficiency<br> ~ Insufficient dopamine<br> ~ Lack of motivation<br> ~ Fatigue<br> ~ Apathy, Inability to feel pleasure<br> ~ Procrastination<br> ~ Low libido<br> ~ Sleep problems<br> ~ Mood swings<br> ~ Hopelessness<br> ~ Memory loss<br> ~ Inability to concentrate<br> Dopamine: Age Related Changes<br> ~ Dopamine levels decline by around 10% per decade from early adulthood and have been associated with declines in cognitive and motor performance<br> ~ Dopamine levels are also impacted by availability of estrogen<br> Dopamine<br> ~ Nutritional building blocks<br> ~ Eating a diet high in magnesium and tyrosine rich foods will ensure you’ve got the basic building blocks needed for dopamine production.<br> ~ Here’s a list of foods known to increase dopamine:</p> <p>Dopamine<br> ~ Medications<br> ~ Most common dopamine antagonists (positive symptoms)<br> ~ Risperdone, Haldol, Zyprexa<br> ~ Metoclopramide (Reglan) is an antiemetic and antipsychotic<br> ~ Most common dopamine AGONISTs (Parkinson’s, Restless Legs) (negative symptoms)<br> ~ Mirapex &amp; Requip</p> <p>Glutamate<br> ~ Is an amino acid (present in most high protein foods)<br> ~ Most prevalent excitatory neurotransmitter<br> ~ Used to make GABA (teeter-totter)<br> ~ Facilitates learning and memory<br> ~ Excess glutamate is associated with<br> ~ Panic attacks / anxiety<br> ~ Impulsivity<br> ~ OCD<br> ~ Depression<br> Glutamate<br> ~ Availability declines with age<br> ~ Affected by serotonin availability<br> ~ Insufficient<br> ~ Agitation<br></p>