FYI - For Your Innovation

Best of 2021 – FYI Podcast Compilation

Meet the Scientists: Dr. Omar Abudayyeh and Dr. Jonathan Gootenberg

Up until recently, DNA has dominated the field of technological development. However, RNA is slowly but surely finding its place on the stage. Although it is more fragile, and therefore more difficult to handle, there are a multitude of benefits to working with RNA over DNA, and in today’s episode we are joined by Dr. David Nelles, who is going to open your mind to the power that lies within these special molecules. David has spent the majority of his career building technologies that recognize and change RNA in human cells, and as you’ll hear today, there are numerous benefits to the development of this kind of technology. In our discussion, we talk about how CRISPR is evolving and why it has taken over from other gene editing techniques, the differences between homology directed repair (HDR) and non homologous end joining (NHEJ), and some of the things that David is most excited about in the future of the incredibly diverse and fascinating RNA field. Key Points From This Episode: Factors that caused CRISPR to dominate the gene editing space. David explains the difference between DNA and RNA, using a football analogy. The goal that David centered his PhD around. Variety that exists amongst RND molecules. Benefits of targeting RNA in diseased cells, rather than DNA. Why RNA lagged behind DNA in terms of technological developments. A theory about the role played by RNA in the past. Methods of RNA editing. Comparing homology directed repair (HDR) and non homologous end joining (NHEJ). David provides a breakdown of the various different guides and enzymes. Three kinds of vector systems, and how they work. Examples of the types of RNAs that exist. What David is excited about in the future of the RNA technology field.

The Creator Economy with Sima Gandhi

The Past, Present, and Future of the COVID 19 Pandemic with Dr. Scott Gottlieb

Invisible Technologies with Francis Pedraza

NFTs with Witek Radomski and Caleb Applegate of Enjin

Therapeutic Human Gene Editing with Dr. David Liu

Cross-Border Payment Disruption with Ham Serunjogi

Nifty Gateway and the Significance of NFTs with Griffin Cock Foster

The ₿ Word — featuring Cathie Wood, Jack Dorsey, and Elon Musk

Online Sports Betting with Will Hershey

The State of Robotaxis in China with Prof. X

Competitive Mobile Gaming with Andrew Paradise, CEO and Founder of Skillz

The Future of Genome Editing with Professor David Liu