Science Signaling Podcast
Summary: Periodic audiocasts from Science Signaling, the leading journal of regulatory biology and cell signaling in physiology and disease
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- Artist: Science Signaling
- Copyright: © 2017 American Association for the Advancement of Science
Podcasts:
Nick Gay discusses how the adaptor protein TMED7 targets the pathogen-sensing receptor TLR4 to the plasma membrane.
Ted Young discusses how a nutrient-sensing kinase inhibits the decay of transcripts encoding proteins that allow cells to utilize non-glucose carbon sources.
Takahiro Ochiya explains how bone marrow mesenchymal stem cells can cause metastatic breast cancer cells to become dormant.
Yong Ho Bae and Richard Assoian discuss a signaling pathway that causes cells to stiffen their cytoskeletons and proliferate when placed on stiff substrates.
Nancy Hynes talks about how a copper-binding enzyme called Memo promotes breast cancer metastasis.
Scott Early talks about a pressure-sensitive signaling pathway that maintains constant blood flow to the brain.
Gideon Schrieber discusses how an engineered form of interferon-α2 stimulates the antiviral response without suppressing cell proliferation or activating immunomodulatory genes.
Renate Pilz discusses an alternative form of the thyroid hormone receptor that mediates nongenomic signaling at the plasma membrane.
Research from Chunling Yi's lab indicates that the progression of a type of KRAS-driven pancreatic cancer requires the transcription factor Yap.
José María González-Granado, Francisco Sánchez-Madrid, and Vicente Andrés have found that a component of the nuclear skeleton modulates signaling through immunological synapses.
Ann-Kathrin Eisfeld and Albert de la Chapelle describe how an oncogenic microRNA drives leukemia progression.
Maurizio Scaltriti explains why a combination therapy that targets the PI3K-Akt pathway and signaling through the growth factor receptors EGFR and HER3 may be effective against triple-negative breast cancer.
Vitezslav Bryja, Reinoud de Groot, and Rik Korswagen discovered that Huwe1 ubiquitylates Dishevelled to negatively regulate Wnt signaling.
Geoffrey Abbot discusses how a potassium channel and a small molecule transporter cooperate to regulate the composition of cerebrospinal fluid and seizure susceptibility.
Mohamed Soliman and Jim Dennis discuss an adaptor protein that decreases glucose uptake and metabolism by inhibiting mTOR signaling.
