Science Signaling Podcast
Summary: Periodic audiocasts from Science Signaling, the leading journal of regulatory biology and cell signaling in physiology and disease
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- Artist: Science Signaling
- Copyright: © 2017 American Association for the Advancement of Science
Podcasts:
Adam Schrum and Steven Neier describe a technique for identifying patient-specific protein complexes and how it revealed altered signaling in T cells from patients with the autoimmune disease alopecia areata.
Steven Wiley describes a quantitative study that shows that adaptor proteins, not core signaling components, control the flow of information through the EGF pathway.
Francisco Quintana describes nanoparticles that inhibit the development of type 1 diabetes in mice by promoting immune tolerance.
Stuart Yuspa explains how increased signaling through the tyrosine kinase receptor MET promotes squamous cell carcinoma.
Kevin Janes explains how a statistical modeling approach was used to discover how insulin signaling can suppress inflammatory signaling.
Benita Katzenellenbogen, John Katzenellenbogen, and Zeynep Madak-Erdogan explain how designer estrogens can deliver the the therapeutic benefits of natural estrogens with less cancer risk.
Alexandra Newton and Rudolph Tanzi explain how activating mutations in a kinase are linked to the pathology of Alzheimer’s disease.
Rachel Golub and Eric Vivier discuss signaling events that control the plasticity of Group 3 innate lymohoid cells.
Mikel Garcia-Marcos explains how mutations in a G protein subunit cause auriculo-condylar syndrome.
Sarah Schumacher and Walter Koch explain how a GRK2-derived peptide reduces pathological cardiac hypertrophy in mice.
Giovanna Tosato explains how a cytokine subunit activates inflammatory signaling inside endothelial cells.
Ivan Bogeski explains how redox-insensitive ORAI calcium channels enable monocytes to sustain calcium signaling while still producing bactericidal reactive oxygen species.
Alan Smrcka explains the distinct contributions that different heterotrimeric G protein subunits make to neutrophil migration.
Claus Jrgensen describes how his group used phosphoproteomic analysis to identify signaling events required for transendothelial migration of metastatic cancer cells.
Jim Casanova describes how a macrophage adhesion receptor both mediates phagocytosis of bacteria and triggers the generation of reactive oxygen species to kill them.
