JNNP podcast

This month, editor Matthew Kiernan discusses new guidelines for recognising central nervous system neuronal surface antibody associated symptoms with Angela Vincent (emeritus professor of neuroimmunology at Oxford University).Danielle Cath (psychiatrist at Altrecht Academic Anxiety Outpatients Clinics, Utrecht University) explains what her review of the relationship between obsessive compulsive disorder and movement disorders reveals.And Charles Warlow (emeritus professor of medical neurology at the University of Edinburgh) looks back on his highly cited 1988 paper on incidence, outcome and type of stroke in Oxfordshire.See also:Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition http://tinyurl.com/avn64slRelationship between movement disorders and obsessive–compulsive disorder: beyond the obsessive–compulsive–tic phenotype. A systematic review http://tinyurl.com/b8vk32gA prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project, 1981–86 http://tinyurl.com/ax26xlk

This month Beau Bruce (assistant professor of ophthalmology and neurology, Emory University School of Medicine, Atlanta) discusses what we do and don’t know about idiopathic intracranial hypertension, and offers some clinical advice on the syndrome for neurologists.And Charles Bolton (professor in the Department of Medicine, Queen’s University, Ontario, Canada) talks us through his investigations in the 1980s which discovered critical illness could cause neurological problems.See also:Update on the pathophysiology and management of idiopathic intracranial hypertension http://tinyurl.com/bhjc9h6Polyneuropathy in critically ill patients http://tinyurl.com/bbze6jc

This month Beau Bruce (assistant professor of ophthalmology and neurology, Emory University School of Medicine, Atlanta) discusses what we do and don’t know about idiopathic intracranial hypertension, and offers some clinical advice on the syndrome for neurologists.And Charles Bolton (professor in the Department of Medicine, Queen’s University, Ontario, Canada) talks us through his investigations in the 1980s which discovered critical illness could cause neurological problems.See also:Update on the pathophysiology and management of idiopathic intracranial hypertension http://tinyurl.com/bhjc9h6Polyneuropathy in critically ill patients http://tinyurl.com/bbze6jc

In April’s podcast, we put a spotlight on amyotrophic lateral sclerosis and frontotemporal dementia.Maxime Bertoux, a neuropsychologist at Paris-Sorbonne University, discusses the problem of misdiagnosis of the behavioural variant of FTD, and how he’s shown the Social Cognition and Emotional Assessment is a more powerful tool than others in use (20.50).And Martin Turner, consultant neurologist at Oxford University Nuffield Department of Clinical Neuroscience, talks about early tractography work in ALS (13.23).We also take a look at corticobasal syndrome. JNNP editor Matthew Kiernan asks John Hodges, Neuroscience Research Australia, about his work looking to standardise diagnostic criteria (1.16).See also:Nerve fibre degeneration in the brain in amyotrophic lateral sclerosis http://tinyurl.com/ar8bolmDiagnostic criteria for corticobasal syndrome: a comparative study http://tinyurl.com/a7sskuxSocial Cognition and Emotional Assessment differentiates frontotemporal dementia from depression http://tinyurl.com/bkpfrruJNNP podcast: Martin Turner on athleticism and ALS http://tinyurl.com/an724hs

In April’s podcast, we put a spotlight on amyotrophic lateral sclerosis and frontotemporal dementia.Maxime Bertoux, a neuropsychologist at Paris-Sorbonne University, discusses the problem of misdiagnosis of the behavioural variant of FTD, and how he’s shown the Social Cognition and Emotional Assessment is a more powerful tool than others in use (20.50).And Martin Turner, consultant neurologist at Oxford University Nuffield Department of Clinical Neuroscience, talks about early tractography work in ALS (13.23).We also take a look at corticobasal syndrome. JNNP editor Matthew Kiernan asks John Hodges, Neuroscience Research Australia, about his work looking to standardise diagnostic criteria (1.16).See also:Nerve fibre degeneration in the brain in amyotrophic lateral sclerosis http://tinyurl.com/ar8bolmDiagnostic criteria for corticobasal syndrome: a comparative study http://tinyurl.com/a7sskuxSocial Cognition and Emotional Assessment differentiates frontotemporal dementia from depression http://tinyurl.com/bkpfrruJNNP podcast: Martin Turner on athleticism and ALS http://tinyurl.com/an724hs

This issue we look at short-term outcomes used to assess multiple sclerosis treatments, and their power to predict long-term disability, with Douglas Goodin (professor of clinical neurology, University of California, San Francisco).We return to the association between cerebral amyloid angiopathy and intracerebral haemorrhage, as Neshika Samarasekera (Division of Clinical Neurosciences, University of Edinburgh) talks us through her research examining the link.And Angela Vincent (emeritus professor at the Nuffield Department of Clinical Neurosciences, University of Oxford) looks back at the beginning of her career investigating autoantibodies in neurological diseases.See also:Relationship between early clinical characteristics and long term disability outcomes: 16 year cohort study (follow-up) of the pivotal interferon β-1b trial in multiple sclerosis http://tinyurl.com/ab7sdd9The association between cerebral amyloid angiopathy and intracerebral haemorrhage: systematic review and meta-analysis http://tinyurl.com/bewdkzfAcetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays http://tinyurl.com/axg6a98

This issue we look at short-term outcomes used to assess multiple sclerosis treatments, and their power to predict long-term disability, with Douglas Goodin (professor of clinical neurology, University of California, San Francisco).We return to the association between cerebral amyloid angiopathy and intracerebral haemorrhage, as Neshika Samarasekera (Division of Clinical Neurosciences, University of Edinburgh) talks us through her research examining the link.And Angela Vincent (emeritus professor at the Nuffield Department of Clinical Neurosciences, University of Oxford) looks back at the beginning of her career investigating autoantibodies in neurological diseases.See also:Relationship between early clinical characteristics and long term disability outcomes: 16 year cohort study (follow-up) of the pivotal interferon β-1b trial in multiple sclerosis http://tinyurl.com/ab7sdd9The association between cerebral amyloid angiopathy and intracerebral haemorrhage: systematic review and meta-analysis http://tinyurl.com/bewdkzfAcetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays http://tinyurl.com/axg6a98

This month, cerebral amyloid angiopathy. David Werring (Stroke Research Group, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery) discusses the importance of detecting it, especially as he feels it is under-recognised by physicians.What impact does a healthy lifestyle have on mortality following stroke? Amytis Towfighi (Division of Stroke and Critical Care, Department of Neurology, University of Southern California) tells us what her research found.And lastly, another dig into the JNNP archives. Mark Hallett (chief of the Human Motor Control Section at the US National Institute of Neurological Disorders and Stroke, NIH) has looked back on his early research on patterns of motor control for the third of our impact commentaries. He talks about how this opened a window onto movement disorder pathophysiology.See also:Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum http://tinyurl.com/anvtsekImpact of a healthy lifestyle on all-cause and cardiovascular mortality after stroke in the USA http://tinyurl.com/b3hjexrEMG analysis of stereotyped voluntary movements in man http://tinyurl.com/a2fvef4

This month, cerebral amyloid angiopathy. David Werring (Stroke Research Group, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery) discusses the importance of detecting it, especially as he feels it is under-recognised by physicians.What impact does a healthy lifestyle have on mortality following stroke? Amytis Towfighi (Division of Stroke and Critical Care, Department of Neurology, University of Southern California) tells us what her research found.And lastly, another dig into the JNNP archives. Mark Hallett (chief of the Human Motor Control Section at the US National Institute of Neurological Disorders and Stroke, NIH) has looked back on his early research on patterns of motor control for the third of our impact commentaries. He talks about how this opened a window onto movement disorder pathophysiology.See also:Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum http://tinyurl.com/anvtsekImpact of a healthy lifestyle on all-cause and cardiovascular mortality after stroke in the USA http://tinyurl.com/b3hjexrEMG analysis of stereotyped voluntary movements in man http://tinyurl.com/a2fvef4

In this first podcast of 2012 editor Matthew Kiernan talks about JNNP’s new impact commentaries - a series which will explore influential papers from the journal. A paper by Simon Wessely (King’s College London) comparing postviral fatigue with that of neuromuscular and affective disorders is the first covered, and he and Matthew discuss this seminal research.Also, Jon Stone (University of Edinburgh) explains what his investigation into the nature of functional weakness onset indicates about the mechanism of the condition.See also:A MODERN PERSPECTIVE ON SOME OF THE MOST HIGHLY CITED JNNP PAPERS OF ALL TIME: The nature of fatigue: a comparison of chronic “postviral” fatigue with neuromuscular and affective disorders http://tinyurl.com/ajr665zWhat is impact? http://tinyurl.com/ah23rzeFunctional weakness: clues to mechanism from the nature of onset http://tinyurl.com/a8c6h33

In this first podcast of 2012 editor Matthew Kiernan talks about JNNP’s new impact commentaries - a series which will explore influential papers from the journal. A paper by Simon Wessely (King’s College London) comparing postviral fatigue with that of neuromuscular and affective disorders is the first covered, and he and Matthew discuss this seminal research.Also, Jon Stone (University of Edinburgh) explains what his investigation into the nature of functional weakness onset indicates about the mechanism of the condition.See also:A MODERN PERSPECTIVE ON SOME OF THE MOST HIGHLY CITED JNNP PAPERS OF ALL TIME: The nature of fatigue: a comparison of chronic “postviral” fatigue with neuromuscular and affective disorders http://tinyurl.com/ajr665zWhat is impact? http://tinyurl.com/ah23rzeFunctional weakness: clues to mechanism from the nature of onset http://tinyurl.com/a8c6h33

This month we discuss the issue of diagnosing delirium in older hospital patients. Despite being linked to a range of poor outcomes, the syndrome is often missed and evidence on its measurement is sparse.Professor Alasdair MacLullich tells us how a device he’s designed with colleagues at the University of Edinburgh, which tests for delirium’s attentional deficits, can benefit clinicians and researchers.See also:Detecting deficits of sustained visual attention in delirium http://tinyurl.com/aswwbaw

This month we discuss the issue of diagnosing delirium in older hospital patients. Despite being linked to a range of poor outcomes, the syndrome is often missed and evidence on its measurement is sparse.Professor Alasdair MacLullich tells us how a device he’s designed with colleagues at the University of Edinburgh, which tests for delirium’s attentional deficits, can benefit clinicians and researchers.See also:Detecting deficits of sustained visual attention in delirium http://tinyurl.com/aswwbaw

In this edition Richard Kanaan (Institute of Psychiatry, King’s College London) talks about his work on conversion disorder, and gives his advice for neurologists and psychiatrists on making this tricky diagnosis.And Vicki Goodwin (Peninsula College of Medicine and Dentistry, University of Exeter) discusses her trial on whether an exercise intervention could prevent falls in those with Parkinson’s disease.See also:Conversion disorder: a problematic diagnosis http://tinyurl.com/agrtdxsAn exercise intervention to prevent falls in people with Parkinson’s disease: a pragmatic randomised controlled trial http://tinyurl.com/b2d697b

In this edition Richard Kanaan (Institute of Psychiatry, King’s College London) talks about his work on conversion disorder, and gives his advice for neurologists and psychiatrists on making this tricky diagnosis.And Vicki Goodwin (Peninsula College of Medicine and Dentistry, University of Exeter) discusses her trial on whether an exercise intervention could prevent falls in those with Parkinson’s disease.See also:Conversion disorder: a problematic diagnosis http://tinyurl.com/agrtdxsAn exercise intervention to prevent falls in people with Parkinson’s disease: a pragmatic randomised controlled trial http://tinyurl.com/b2d697b