Stuart Schweitzer is a professor in the Department of Health Services at the UCLA School of Public Health, Los Angeles. Rachel Gotbaum is an independent producer based in Boston. Supplement to: Schweitzer SO. Trying Times at the FDA -- The Challenge of Ensuring the Safety of Imported Pharmaceuticals. N Engl J Med 2008;358:1773-7.

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Stuart Schweitzer discusses challenges and recent crises at the FDA and the scope of the agency's responsibilities.

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Sherry Glied is a professor and chair of the Department of Health Policy and Management, Mailman School of Public Health, Columbia University, New York. Rachel Gotbaum is an independent producer based in Boston. Supplement to: Glied SA. Universal Coverage One Head at a Time -- The Risks and Benefits of Individual Health Insurance Mandates. N Engl J Med 2008;358:1540-2.

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The health insurance reform enacted in Massachusetts in 2006 and the proposals of the leading Democratic presidential candidates seek to achieve universal health insurance coverage while relying primarily on private insurance. Achieving universality is a challenge in any system that assigns insurance coverage, whether private or public...

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David Hemenway is a professor of health policy at the Harvard School of Public Health, Boston. Rachel Gotbaum is an independent producer based in Boston. Supplement to: Curfman GD, Morrissey S, and Drazen JM. Handgun Violence, Public Health, and the Law. N Engl J Med 2008;358. DOI: 10.1056/NEJMe0802118.

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On March 18, the Supreme Court heard oral arguments in the case of District of Columbia v. Heller, a case challenging handgun control statutes adopted in 1976.

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Mohamed Ali is a statistician in the Department of Measurement and Health Information Systems at the World Health Organization in Geneva, Switzerland. Rachel Gotbaum is an independent producer based in Boston. Supplement to: Brownstein CA and Brownstein JS. Estimating Excess Mortality in Post-Invasion Iraq. N Engl J Med 2008;358:445-7.

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There is no set formula for accurately tallying deaths from humanitarian crises. When a population becomes destabilized, estimation of mortality is likely to be severely challenged.

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On January 7, the Supreme Court heard oral arguments about lethal injection in Baze v. Rees. The Journal presents a video roundtable discussion, moderated by Dr. Atul Gawande, about lethal injection, the three-drug protocol used, and the involvement of health care professionals in capital punishment.

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Peggy Porter is a cancer biology researcher at the Fred Hutchinson Cancer Research Center and a professor of pathology at the University of Washington School of Medicine, Seattle. Rachel Gotbaum, the interviewer, is an independent producer based in Boston. Supplement to: Porter P. "Westernizing" Women's Risks? Breast Cancer in Lower-Income Countries. N Engl J Med 2008;358:213-6.

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Recent media reports have highlighted the increasing incidence of breast cancer in low- and middle-income countries. Although the disease continues to be most prominent in affluent countries, the risks of both breast cancer and death due to breast cancer are clearly increasing worldwide.

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Muin Khoury is the director of the National Office of Public Health Genomics at the Centers for Disease Control and Prevention, Atlanta. Rachel Gotbaum, the interviewer, is an independent producer based in Boston. Supplement to: Hunter DJ, Khoury MJ, and Drazen JM. Letting the Genome out of the Bottle - Will We Get Our Wish? N Engl J Med 2008;358(2):105-7.

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A patient shows up in your office with an analysis of his whole genome at multiple single-nucleotide polymorphisms (SNPs). What should you do? David Hunter, Dr. Muin Khoury, and Dr. Jeffrey Drazen discuss the analytic and clinical validity of personal genomics testing.

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Dr. Thomas Lee is network president for Partners Healthcare in Boston. Rachel Gotbaum, the interviewer, is an independent producer based in Boston. Supplement to: Milstein A and Lee TH. Comparing Physicians on Efficiency. N Engl J Med 2007;357(26):2649-52.

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What are the controversies surrounding the use of physician-efficiency assessments by consumers and purchasers? Can reasonable compromises be struck between physicians and these two kinds of customers?

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Gretchen Berland is an assistant professor of medicine at Yale University School of Medicine, New Haven, CT. Galen Buckwalter is vice president of research and development at eHarmony.com. Rachel Gotbaum, the interviewer, is an independent producer based in Boston. Supplement to: Berland G. The View from the Other Side -- Patients, Doctors, and the Power of a Camera. N Engl J Med 2007;357(25):2533-6.

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Dr. Gretchen Berland gave video cameras to volunteers in wheelchairs in order to understand the experience of being disabled. She writes that the project taught her to see the world in ways she had never imagined.

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